XLF and H2AX function in series to promote replication fork stability

XRCC4-like factor (XLF) is a non-homologous end joining (NHEJ) DNA double strand break repair protein. However, XLF deficiency leads to phenotypes in mice and humans that are not necessarily consistent with an isolated defect in NHEJ. Here we show that XLF functions during DNA replication. XLF under...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Chen, Bo-Ruei, Quinet, Annabel, Byrum, Andrea K., Jackson, Jessica, Berti, Matteo, Thangavel, Saravanabhavan, Bredemeyer, Andrea L., Hindi, Issa, Mosammaparast, Nima, Tyler, Jessica K., Vindigni, Alessandro, Sleckman, Barry P.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605786/
https://ncbi.nlm.nih.gov/pubmed/31123184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201808134
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados