DNA2 drives processing and restart of reversed replication forks in human cells

Accurate processing of stalled or damaged DNA replication forks is paramount to genomic integrity and recent work points to replication fork reversal and restart as a central mechanism to ensuring high-fidelity DNA replication. Here, we identify a novel DNA2- and WRN-dependent mechanism of reversed...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Biol
Auteurs principaux: Thangavel, Saravanabhavan, Berti, Matteo, Levikova, Maryna, Pinto, Cosimo, Gomathinayagam, Shivasankari, Vujanovic, Marko, Zellweger, Ralph, Moore, Hayley, Lee, Eu Han, Hendrickson, Eric A., Cejka, Petr, Stewart, Sheila, Lopes, Massimo, Vindigni, Alessandro
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2015
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347643/
https://ncbi.nlm.nih.gov/pubmed/25733713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406100
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