DNA2 drives processing and restart of reversed replication forks in human cells

Accurate processing of stalled or damaged DNA replication forks is paramount to genomic integrity and recent work points to replication fork reversal and restart as a central mechanism to ensuring high-fidelity DNA replication. Here, we identify a novel DNA2- and WRN-dependent mechanism of reversed...

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Dettagli Bibliografici
Pubblicato in:J Cell Biol
Autori principali: Thangavel, Saravanabhavan, Berti, Matteo, Levikova, Maryna, Pinto, Cosimo, Gomathinayagam, Shivasankari, Vujanovic, Marko, Zellweger, Ralph, Moore, Hayley, Lee, Eu Han, Hendrickson, Eric A., Cejka, Petr, Stewart, Sheila, Lopes, Massimo, Vindigni, Alessandro
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2015
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347643/
https://ncbi.nlm.nih.gov/pubmed/25733713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406100
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