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β-Secretase BACE1 Regulates Hippocampal and Reconstituted M-Currents in a β-Subunit-Like Fashion

The β-secretase BACE1 is widely known for its pivotal role in the amyloidogenic pathway leading to Alzheimer's disease, but how its action on transmembrane proteins other than the amyloid precursor protein affects the nervous system is only beginning to be understood. We report here that BACE1...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hessler, Sabine, Zheng, Fang, Hartmann, Stephanie, Rittger, Andrea, Lehnert, Sandra, Völkel, Meike, Nissen, Matthias, Edelmann, Elke, Saftig, Paul, Schwake, Michael, Huth, Tobias, Alzheimer, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605557/
https://ncbi.nlm.nih.gov/pubmed/25716831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3127-14.2015
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