β-Secretase BACE1 Regulates Hippocampal and Reconstituted M-Currents in a β-Subunit-Like Fashion

The β-secretase BACE1 is widely known for its pivotal role in the amyloidogenic pathway leading to Alzheimer's disease, but how its action on transmembrane proteins other than the amyloid precursor protein affects the nervous system is only beginning to be understood. We report here that BACE1...

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發表在:J Neurosci
Main Authors: Hessler, Sabine, Zheng, Fang, Hartmann, Stephanie, Rittger, Andrea, Lehnert, Sandra, Völkel, Meike, Nissen, Matthias, Edelmann, Elke, Saftig, Paul, Schwake, Michael, Huth, Tobias, Alzheimer, Christian
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605557/
https://ncbi.nlm.nih.gov/pubmed/25716831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3127-14.2015
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