β-Secretase BACE1 Promotes Surface Expression and Function of Kv3.4 at Hippocampal Mossy Fiber Synapses

The β-secretase β-site APP-cleaving enzyme 1 (BACE1) is deemed a major culprit in Alzheimer's disease, but accumulating evidence indicates that there is more to the enzyme than driving the amyloidogenic processing of the amyloid precursor protein. For example, BACE1 has emerged as an important...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hartmann, Stephanie, Zheng, Fang, Kyncl, Michele C., Karch, Sandra, Voelkl, Kerstin, Zott, Benedikt, D'Avanzo, Carla, Lomoio, Selene, Tesco, Giuseppina, Kim, Doo Y., Alzheimer, Christian, Huth, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895038/
https://ncbi.nlm.nih.gov/pubmed/29507146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2643-17.2018
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