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Tyrosine kinase activation and conformational flexibility: Lessons from Src-family tyrosine kinases

Protein kinases are enzymes that catalyze the covalent transfer of γ-phosphate of an adenosine triphosphate (ATP) molecule onto a tyrosine, serine, threonine, or histidine residue in the substrate, and thus send a chemical signal to networks of downstream proteins. They are important cellular signal...

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Dades bibliogràfiques
Publicat a:Acc Chem Res
Autors principals: Meng, Yilin, Pond, Matthew P., Roux, Benoît
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602532/
https://ncbi.nlm.nih.gov/pubmed/28426203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.7b00012
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