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Tyrosine kinase activation and conformational flexibility: Lessons from Src-family tyrosine kinases
Protein kinases are enzymes that catalyze the covalent transfer of γ-phosphate of an adenosine triphosphate (ATP) molecule onto a tyrosine, serine, threonine, or histidine residue in the substrate, and thus send a chemical signal to networks of downstream proteins. They are important cellular signal...
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| Published in: | Acc Chem Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602532/ https://ncbi.nlm.nih.gov/pubmed/28426203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.accounts.7b00012 |
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