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Computational Study of the “DFG-Flip” Conformational Transition in c-Abl and c-Src Tyrosine Kinases

[Image: see text] Protein tyrosine kinases are crucial to cellular signaling pathways regulating cell growth, proliferation, metabolism, differentiation, and migration. To maintain normal regulation of cellular signal transductions, the activities of tyrosine kinases are also highly regulated. The c...

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Bibliografiset tiedot
Julkaisussa:J Phys Chem B
Päätekijät: Meng, Yilin, Lin, Yen-lin, Roux, Benoît
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2014
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315421/
https://ncbi.nlm.nih.gov/pubmed/25548962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp511792a
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