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Computational Study of the “DFG-Flip” Conformational Transition in c-Abl and c-Src Tyrosine Kinases
[Image: see text] Protein tyrosine kinases are crucial to cellular signaling pathways regulating cell growth, proliferation, metabolism, differentiation, and migration. To maintain normal regulation of cellular signal transductions, the activities of tyrosine kinases are also highly regulated. The c...
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| Published in: | J Phys Chem B |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Chemical
Society
2014
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315421/ https://ncbi.nlm.nih.gov/pubmed/25548962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp511792a |
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