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Computational Study of the “DFG-Flip” Conformational Transition in c-Abl and c-Src Tyrosine Kinases

[Image: see text] Protein tyrosine kinases are crucial to cellular signaling pathways regulating cell growth, proliferation, metabolism, differentiation, and migration. To maintain normal regulation of cellular signal transductions, the activities of tyrosine kinases are also highly regulated. The c...

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Bibliografiska uppgifter
I publikationen:J Phys Chem B
Huvudupphovsmän: Meng, Yilin, Lin, Yen-lin, Roux, Benoît
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2014
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315421/
https://ncbi.nlm.nih.gov/pubmed/25548962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp511792a
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