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Computational Study of the “DFG-Flip” Conformational Transition in c-Abl and c-Src Tyrosine Kinases
[Image: see text] Protein tyrosine kinases are crucial to cellular signaling pathways regulating cell growth, proliferation, metabolism, differentiation, and migration. To maintain normal regulation of cellular signal transductions, the activities of tyrosine kinases are also highly regulated. The c...
Gardado en:
| Publicado en: | J Phys Chem B |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2014
|
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4315421/ https://ncbi.nlm.nih.gov/pubmed/25548962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp511792a |
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