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Computational study of the W260A activating mutant of Src tyrosine kinase
Tyrosine kinases are enzymes playing a critical role in cellular signaling. Mutations causing increased in kinase activity are often associated with cancer and various pathologies. One example in Src tyrosine kinases is offered by the substitution of the highly conserved tryptophan 260 by an alanine...
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| Vydáno v: | Protein Sci |
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| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
John Wiley and Sons Inc.
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4815304/ https://ncbi.nlm.nih.gov/pubmed/26106037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2731 |
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