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Computational study of the W260A activating mutant of Src tyrosine kinase
Tyrosine kinases are enzymes playing a critical role in cellular signaling. Mutations causing increased in kinase activity are often associated with cancer and various pathologies. One example in Src tyrosine kinases is offered by the substitution of the highly conserved tryptophan 260 by an alanine...
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| 出版年: | Protein Sci |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4815304/ https://ncbi.nlm.nih.gov/pubmed/26106037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2731 |
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