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Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives
Postsynaptic N-methyl-d-aspartate receptors (NMDARs) phasically activated by presynaptically released glutamate are critical for synaptic transmission and plasticity. However, under pathological conditions, excessive activation of NMDARs by tonically increased ambient glutamate contributes to excito...
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| Vydáno v: | J Neurosci |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6602038/ https://ncbi.nlm.nih.gov/pubmed/26888927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3181-15.2016 |
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