Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives

Postsynaptic N-methyl-d-aspartate receptors (NMDARs) phasically activated by presynaptically released glutamate are critical for synaptic transmission and plasticity. However, under pathological conditions, excessive activation of NMDARs by tonically increased ambient glutamate contributes to excito...

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Publicat a:J Neurosci
Autors principals: Vyklicky, Vojtech, Smejkalova, Tereza, Krausova, Barbora, Balik, Ales, Korinek, Miloslav, Borovska, Jirina, Horak, Martin, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Cerny, Jiri, Nekardova, Michaela, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602038/
https://ncbi.nlm.nih.gov/pubmed/26888927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3181-15.2016
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