Cholesterol modulates open probability and desensitization of NMDA receptors

NMDA receptors (NMDARs) are glutamate-gated ion channels that mediate excitatory neurotransmission in the CNS. Although these receptors are in direct contact with plasma membrane, lipid–NMDAR interactions are little understood. In the present study, we aimed at characterizing the effect of cholester...

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Dettagli Bibliografici
Pubblicato in:J Physiol
Autori principali: Korinek, Miloslav, Vyklicky, Vojtech, Borovska, Jirina, Lichnerova, Katarina, Kaniakova, Martina, Krausova, Barbora, Krusek, Jan, Balik, Ales, Smejkalova, Tereza, Horak, Martin, Vyklicky, Ladislav
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2015
Soggetti:
Neuroscience: Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457192/
https://ncbi.nlm.nih.gov/pubmed/25651798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.288209
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