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Key Amino Acid Residues within the Third Membrane Domains of NR1 and NR2 Subunits Contribute to the Regulation of the Surface Delivery of N-methyl-d-aspartate Receptors

N-methyl-d-aspartate (NMDA) receptors are glutamate ionotropic receptors that play critical roles in synaptic transmission, plasticity, and excitotoxicity. The functional NMDA receptors, heterotetramers composed mainly of two NR1 and two NR2 subunits, likely pass endoplasmic reticulum quality contro...

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Detalhes bibliográficos
Main Authors: Kaniakova, Martina, Krausova, Barbora, Vyklicky, Vojtech, Korinek, Miloslav, Lichnerova, Katarina, Vyklicky, Ladislav, Horak, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3406725/
https://ncbi.nlm.nih.gov/pubmed/22711533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339085
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