Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit

N-methyl-D-aspartate receptors (NMDARs), glutamate-gated ion channels, mediate signaling at the majority of excitatory synapses in the nervous system. Recent sequencing data for neurological and psychiatric patients have indicated numerous mutations in genes encoding for NMDAR subunits. Here, we pre...

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Pubblicato in:Front Mol Neurosci
Autori principali: Vyklicky, Vojtech, Krausova, Barbora, Cerny, Jiri, Ladislav, Marek, Smejkalova, Tereza, Kysilov, Bohdan, Korinek, Miloslav, Danacikova, Sarka, Horak, Martin, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897658/
https://ncbi.nlm.nih.gov/pubmed/29681796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00110
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