Surface Expression, Function, and Pharmacology of Disease-Associated Mutations in the Membrane Domain of the Human GluN2B Subunit

N-methyl-D-aspartate receptors (NMDARs), glutamate-gated ion channels, mediate signaling at the majority of excitatory synapses in the nervous system. Recent sequencing data for neurological and psychiatric patients have indicated numerous mutations in genes encoding for NMDAR subunits. Here, we pre...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Vyklicky, Vojtech, Krausova, Barbora, Cerny, Jiri, Ladislav, Marek, Smejkalova, Tereza, Kysilov, Bohdan, Korinek, Miloslav, Danacikova, Sarka, Horak, Martin, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5897658/
https://ncbi.nlm.nih.gov/pubmed/29681796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00110
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