Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor

N-methyl-D-aspartate receptor (NMDAR) hypofunction has been implicated in several neurodevelopmental disorders. NMDAR function can be augmented by positive allosteric modulators, including endogenous compounds, such as cholesterol and neurosteroid pregnenolone sulfate (PES). Here we report that PES...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hrcka Krausova, Barbora, Kysilov, Bohdan, Cerny, Jiri, Vyklicky, Vojtech, Smejkalova, Tereza, Ladislav, Marek, Balik, Ales, Korinek, Miloslav, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392504/
https://ncbi.nlm.nih.gov/pubmed/32611707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3010-19.2020
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