Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor

N-methyl-D-aspartate receptor (NMDAR) hypofunction has been implicated in several neurodevelopmental disorders. NMDAR function can be augmented by positive allosteric modulators, including endogenous compounds, such as cholesterol and neurosteroid pregnenolone sulfate (PES). Here we report that PES...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Hrcka Krausova, Barbora, Kysilov, Bohdan, Cerny, Jiri, Vyklicky, Vojtech, Smejkalova, Tereza, Ladislav, Marek, Balik, Ales, Korinek, Miloslav, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2020
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7392504/
https://ncbi.nlm.nih.gov/pubmed/32611707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3010-19.2020
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