Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives

Postsynaptic N-methyl-d-aspartate receptors (NMDARs) phasically activated by presynaptically released glutamate are critical for synaptic transmission and plasticity. However, under pathological conditions, excessive activation of NMDARs by tonically increased ambient glutamate contributes to excito...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Vyklicky, Vojtech, Smejkalova, Tereza, Krausova, Barbora, Balik, Ales, Korinek, Miloslav, Borovska, Jirina, Horak, Martin, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Cerny, Jiri, Nekardova, Michaela, Chodounska, Hana, Kudova, Eva, Vyklicky, Ladislav
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602038/
https://ncbi.nlm.nih.gov/pubmed/26888927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3181-15.2016
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