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Location is the key to function: HMGB1 in sepsis and trauma-induced inflammation
HMGB1 is a multifunctional nuclear protein, probably known best as a prototypical alarmin or damage-associated molecular pattern (DAMP) molecule when released from cells. However, HMGB1 has multiple functions that depend on its location in the nucleus, in the cytosol, or extracellularly after either...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Leukoc Biol |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6597316/ https://ncbi.nlm.nih.gov/pubmed/30946496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.3MIR1218-497R |
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