Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type–Specific Functions of TLR4 during Sepsis

The morbidity associated with bacterial sepsis is the result of host immune responses to pathogens, which are dependent on pathogen recognition by pattern recognition receptors, such as TLR4. TLR4 is expressed on a range of cell types, yet the mechanisms by which cell-specific functions of TLR4 lead...

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Hlavní autoři: Deng, Meihong, Scott, Melanie J., Loughran, Patricia, Gibson, Gregory, Sodhi, Chhinder, Watkins, Simon, Hackam, David, Billiar, Timothy R.
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2013
Témata:
Infectious Disease and Host Response
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644895/
https://ncbi.nlm.nih.gov/pubmed/23562812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300496
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