Lipopolysaccharide Clearance, Bacterial Clearance, and Systemic Inflammatory Responses Are Regulated by Cell Type–Specific Functions of TLR4 during Sepsis

The morbidity associated with bacterial sepsis is the result of host immune responses to pathogens, which are dependent on pathogen recognition by pattern recognition receptors, such as TLR4. TLR4 is expressed on a range of cell types, yet the mechanisms by which cell-specific functions of TLR4 lead...

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Bibliografiske detaljer
Main Authors: Deng, Meihong, Scott, Melanie J., Loughran, Patricia, Gibson, Gregory, Sodhi, Chhinder, Watkins, Simon, Hackam, David, Billiar, Timothy R.
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2013
Fag:
Infectious Disease and Host Response
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644895/
https://ncbi.nlm.nih.gov/pubmed/23562812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300496
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