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Genetic Deletion of TLR4 on Platelets Attenuates Experimental Pulmonary Hypertension

RATIONALE: Recent studies demonstrate a role for TLR4 in the pathogenesis of pulmonary hypertension (PH), however, the cell types involved in mediating the effects of TLR4 remain unknown. OBJECTIVES: The objective of this study was to determine the contribution of TLR4 expressed on nonparenchymal ce...

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Detalhes bibliográficos
Main Authors: Bauer, Eileen M., Chanthaphavong, R. Savanh, Sodhi, Chhinder P., Hackam, David J., Billiar, Timothy, Bauer, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041329/
https://ncbi.nlm.nih.gov/pubmed/24637196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.114.303662
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