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Myocyte TLR4 enhances enteric and systemic inflammation driving late murine endotoxic ileus

Myocytes are nonhemopoietic in origin and functionally essential in generating gastrointestinal motility. In endotoxemia, a rapid-onset nonhemopoietic mechanism potently triggers early ileus in a Toll-like receptor 4 (TLR4)/myeloid differentiation primary response gene 88 (MyD88)-dependent manner. M...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Buchholz, Bettina M., Shapiro, Richard A., Vodovotz, Yoram, Billiar, Timothy R., Sodhi, Chhinder P., Hackam, David J., Bauer, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437022/
https://ncbi.nlm.nih.gov/pubmed/25747352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00211.2014
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