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Dominant role of the MyD88-dependent signaling pathway in mediating early endotoxin-induced murine ileus

TLR4 ligation by pathogen-associated molecular patterns, such as Gram-negative bacteria-derived LPS, triggers a nonhematopoietic cell-mediated ileus during early endotoxemia. Our objective was to investigate the quantitative contributions of the two downstream signaling pathways of TLR4, namely the...

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Hlavní autoři: Buchholz, Bettina M., Billiar, Timothy R., Bauer, Anthony J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928536/
https://ncbi.nlm.nih.gov/pubmed/20508155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00060.2010
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