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Role of Interleukin-6 in Hemopoietic and Non-hemopoietic Synergy mediating TLR4-triggered Late Murine Ileus and Endotoxic Shock

BACKGROUND: Early murine endotoxin-induced ileus at 6 hours is exclusively mediated by non-hemopoietic TLR4/MyD88 signaling despite molecular activation of hemopoietic cells which included a significant IL-6 mRNA induction. Our objective was to define the role of hemopoietic cells in LPS/TLR4-trigge...

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Autori principali: Buchholz, Bettina M., Chanthaphavong, R. Savanh, Billiar, Timothy R., Bauer, Anthony J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378783/
https://ncbi.nlm.nih.gov/pubmed/22489868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2012.01914.x
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