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Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis
Gasdermin D (GsdmD) was recently identified as the executioner of pyroptotic inflammatory cell death, and is a substrate for caspases-1 and 11. GsdmD is detrimental in lethal endotoxemia but protective in bacterial sepsis. However, little is known about its role during noninfectious/sterile injuries...
Zapisane w:
| Wydane w: | Cell Death Dis |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Publishing Group UK
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6579760/ https://ncbi.nlm.nih.gov/pubmed/31209224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1719-6 |
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