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Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

BACKGROUND: Hepatic ischemia/reperfusion (I/R) injury can be a major complication following liver surgery contributing to post-operative liver dysfunction. Maresin 1 (MaR1), a pro-resolving lipid mediator, has been shown to suppress I/R injury. However, the mechanisms that account for the protective...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Tang, Da, Fu, Guang, Li, Wenbo, Sun, Ping, Loughran, Patricia A., Deng, Meihong, Scott, Melanie J., Billiar, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7905895/
https://ncbi.nlm.nih.gov/pubmed/33632134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10020-021-00280-9
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