cGAS-mediated autophagy protects the liver from ischemia-reperfusion injury independently of STING

Liver ischemia-reperfusion (I/R) injury occurs through induction of oxidative stress and release of damage-associated molecular patterns (DAMPs), including cytosolic DNA released from dysfunctional mitochondria or from the nucleus. Cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) synth...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Lei, Zhao, Deng, Meihong, Yi, Zhongjie, Sun, Qian, Shapiro, Richard A., Xu, Hongbo, Li, Tunliang, Loughran, Patricia A., Griepentrog, John E., Huang, Hai, Scott, Melanie J., Huang, Feizhou, Billiar, Timothy R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032062/
https://ncbi.nlm.nih.gov/pubmed/29446653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00326.2017
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