Wiskott–Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma

In T lymphocytes WASP and WIP regulate TCR signaling but their role in lymphoma is largely unknown. Here we show that the expression of WASP and WIP is frequently low or absent in anaplastic large cell lymphoma (ALCL) compared to other T cell lymphomas. In ALK+ ALCL, WASP and WIP expression is regul...

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Опубликовано в: :Nat Med
Главные авторы: Menotti, Matteo, Ambrogio, Chiara, Cheong, Taek-Chin, Pighi, Chiara, Mota, Ines, Cassel, Seth H., Compagno, Mara, Wang, Qi, Dall’Olio, Riccardo, Minero, Valerio, Poggio, Teresa, Sharma, Geeta Geeta, Patrucco, Enrico, Mastini, Cristina, Choudhari, Ramesh, Pich, Achille, Zamo’, Alberto, Piva, Roberto, Giliani, Silvia, Mologni, Luca, Collings, Clayton K., Kadoch, Cigall, Gambacorti-Passerini, Carlo, Notarangelo, Luigi D., Anton, Ines M., Voena, Claudia, Chiarle, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556382/
https://ncbi.nlm.nih.gov/pubmed/30510251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0262-9
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