Wiskott–Aldrich syndrome protein (WASP) is a tumor suppressor in T cell lymphoma

In T lymphocytes WASP and WIP regulate TCR signaling but their role in lymphoma is largely unknown. Here we show that the expression of WASP and WIP is frequently low or absent in anaplastic large cell lymphoma (ALCL) compared to other T cell lymphomas. In ALK+ ALCL, WASP and WIP expression is regul...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Med
Prif Awduron: Menotti, Matteo, Ambrogio, Chiara, Cheong, Taek-Chin, Pighi, Chiara, Mota, Ines, Cassel, Seth H., Compagno, Mara, Wang, Qi, Dall’Olio, Riccardo, Minero, Valerio, Poggio, Teresa, Sharma, Geeta Geeta, Patrucco, Enrico, Mastini, Cristina, Choudhari, Ramesh, Pich, Achille, Zamo’, Alberto, Piva, Roberto, Giliani, Silvia, Mologni, Luca, Collings, Clayton K., Kadoch, Cigall, Gambacorti-Passerini, Carlo, Notarangelo, Luigi D., Anton, Ines M., Voena, Claudia, Chiarle, Roberto
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556382/
https://ncbi.nlm.nih.gov/pubmed/30510251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-018-0262-9
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