Efficacy of a cancer vaccine against ALK-rearranged lung tumors

Non-small cell lung cancer (NSCLC) harboring chromosomal rearrangements of the anaplastic lymphoma kinase (ALK) gene is treated with ALK tyrosine kinase inhibitors (TKIs), but is successful for only a limited amount of time; most cases relapse due to the development of drug resistance. Here we show...

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Vydáno v:Cancer Immunol Res
Hlavní autoři: Voena, Claudia, Menotti, Matteo, Mastini, Cristina, Di Giacomo, Filomena, Longo, Dario Livio, Castella, Barbara, Merlo, Maria Elena Boggio, Ambrogio, Chiara, Wang, Qi, Minero, Valerio Giacomo, Poggio, Teresa, Martinengo, Cinzia, D'Amico, Lucia, Panizza, Elena, Mologni, Luca, Cavallo, Federica, Altruda, Fiorella, Butaney, Mohit, Capelletti, Marzia, Inghirami, Giorgio, Jänne, Pasi A., Chiarle, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674335/
https://ncbi.nlm.nih.gov/pubmed/26419961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0089
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