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The Anaplastic Lymphoma Kinase controls cell shape and growth of Anaplastic Large Cell Lymphoma through Cdc42 activation

Anaplastic Large Cell Lymphoma (ALCL) is a Non-Hodgkin Lymphoma (NHL) that originates from T cells and frequently expresses oncogenic fusion proteins derived from chromosomal translocations or inversions of the Anaplastic Lymphoma Kinase (ALK) gene. Proliferation and survival of ALCL cells are deter...

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Библиографические подробности
Главные авторы: Ambrogio, Chiara, Voena, Claudia, Manazza, Andrea D., Martinengo, Cinzia, Costa, Carlotta, Kirchhausen, Tomas, Hirsch, Emilio, Inghirami, Giorgio, Chiarle, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596920/
https://ncbi.nlm.nih.gov/pubmed/18974134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2568
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