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p130Cas mediates the transforming properties of the anaplastic lymphoma kinase
Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in stromal tumors. The most frequent translocation, t(2;5), generates the fusion protein nucleophosmin (NPM)–ALK with intrinsic tyrosine kinase activity. Along with transfor...
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
© 2005 by The American Society of Hematology
2005
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895100/ https://ncbi.nlm.nih.gov/pubmed/16105984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1204 |
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