p130Cas mediates the transforming properties of the anaplastic lymphoma kinase

Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in stromal tumors. The most frequent translocation, t(2;5), generates the fusion protein nucleophosmin (NPM)–ALK with intrinsic tyrosine kinase activity. Along with transfor...

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Bibliografiska uppgifter
Huvudupphovsmän: Ambrogio, Chiara, Voena, Claudia, Manazza, Andrea D., Piva, Roberto, Riera, Ludovica, Barberis, Laura, Costa, Carlotta, Tarone, Guido, Defilippi, Paola, Hirsch, Emilio, Erba, Elisabetta Boeri, Mohammed, Shabaz, Jensen, Ole N., Palestro, Giorgio, Inghirami, Giorgio, Chiarle, Roberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: © 2005 by The American Society of Hematology 2005
Ämnen:
Neoplasia
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895100/
https://ncbi.nlm.nih.gov/pubmed/16105984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1204
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