p130Cas mediates the transforming properties of the anaplastic lymphoma kinase

Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in stromal tumors. The most frequent translocation, t(2;5), generates the fusion protein nucleophosmin (NPM)–ALK with intrinsic tyrosine kinase activity. Along with transfor...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ambrogio, Chiara, Voena, Claudia, Manazza, Andrea D., Piva, Roberto, Riera, Ludovica, Barberis, Laura, Costa, Carlotta, Tarone, Guido, Defilippi, Paola, Hirsch, Emilio, Erba, Elisabetta Boeri, Mohammed, Shabaz, Jensen, Ole N., Palestro, Giorgio, Inghirami, Giorgio, Chiarle, Roberto
Format: Artigo
Langue:Inglês
Publié: © 2005 by The American Society of Hematology 2005
Sujets:
Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895100/
https://ncbi.nlm.nih.gov/pubmed/16105984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1204
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