p130Cas mediates the transforming properties of the anaplastic lymphoma kinase

Translocations of the anaplastic lymphoma kinase (ALK) gene have been described in anaplastic large-cell lymphomas (ALCLs) and in stromal tumors. The most frequent translocation, t(2;5), generates the fusion protein nucleophosmin (NPM)–ALK with intrinsic tyrosine kinase activity. Along with transfor...

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Detalhes bibliográficos
Main Authors: Ambrogio, Chiara, Voena, Claudia, Manazza, Andrea D., Piva, Roberto, Riera, Ludovica, Barberis, Laura, Costa, Carlotta, Tarone, Guido, Defilippi, Paola, Hirsch, Emilio, Erba, Elisabetta Boeri, Mohammed, Shabaz, Jensen, Ole N., Palestro, Giorgio, Inghirami, Giorgio, Chiarle, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895100/
https://ncbi.nlm.nih.gov/pubmed/16105984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1204
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