Oncogenic ALK regulates EMT in non-small cell lung carcinoma through repression of the epithelial splicing regulatory protein 1

A subset of Non-Small Cell Lung Carcinoma (NSCLC) carries chromosomal rearrangements involving the Anaplastic Lymphoma Kinase (ALK) gene. ALK-rearranged NSCLC are typically adenocarcinoma characterized by a solid signet-ring cell pattern that is frequently associated with a metastatic phenotype. Rec...

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Pubblicato in:Oncotarget
Autori principali: Voena, Claudia, Varesio, Lydia M., Zhang, Liye, Menotti, Matteo, Poggio, Teresa, Panizza, Elena, Wang, Qi, Minero, Valerio G., Fagoonee, Sharmila, Compagno, Mara, Altruda, Fiorella, Monti, Stefano, Chiarle, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078097/
https://ncbi.nlm.nih.gov/pubmed/27119231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8955
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