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Tumor Resistance against ALK Targeted Therapy-Where It Comes From and Where It Goes
Anaplastic lymphoma kinase (ALK) is a validated molecular target in several ALK-rearranged malignancies, particularly in non-small-cell lung cancer (NSCLC), which has generated considerable interest and effort in developing ALK tyrosine kinase inhibitors (TKI). Crizotinib was the first ALK inhibitor...
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Publicado no: | Cancers (Basel) |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
MDPI
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5876637/ https://ncbi.nlm.nih.gov/pubmed/29495603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10030062 |
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