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PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection of the host genome sequence while allowing for ef...

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Detalles Bibliográficos
Publicado en:RNA Biol
Main Authors: Gleditzsch, Daniel, Pausch, Patrick, Müller-Esparza, Hanna, Özcan, Ahsen, Guo, Xiaohan, Bange, Gert, Randau, Lennart
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546366/
https://ncbi.nlm.nih.gov/pubmed/30109815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1504546
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