PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection of the host genome sequence while allowing for ef...

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發表在:RNA Biol
Main Authors: Gleditzsch, Daniel, Pausch, Patrick, Müller-Esparza, Hanna, Özcan, Ahsen, Guo, Xiaohan, Bange, Gert, Randau, Lennart
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2018
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546366/
https://ncbi.nlm.nih.gov/pubmed/30109815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1504546
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