PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection of the host genome sequence while allowing for ef...

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Dades bibliogràfiques
Publicat a:RNA Biol
Autors principals: Gleditzsch, Daniel, Pausch, Patrick, Müller-Esparza, Hanna, Özcan, Ahsen, Guo, Xiaohan, Bange, Gert, Randau, Lennart
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2018
Matèries:
Review
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546366/
https://ncbi.nlm.nih.gov/pubmed/30109815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1504546
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