PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection of the host genome sequence while allowing for ef...

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Dettagli Bibliografici
Pubblicato in:RNA Biol
Autori principali: Gleditzsch, Daniel, Pausch, Patrick, Müller-Esparza, Hanna, Özcan, Ahsen, Guo, Xiaohan, Bange, Gert, Randau, Lennart
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2018
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546366/
https://ncbi.nlm.nih.gov/pubmed/30109815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1504546
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