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Anti-CRISPR AcrIF9 functions by inducing the CRISPR–Cas complex to bind DNA non-specifically

Phages and other mobile genetic elements express anti-CRISPR proteins (Acrs) to protect their genomes from destruction by CRISPR–Cas systems. Acrs usually block the ability of CRISPR–Cas systems to bind or cleave their nucleic acid substrates. Here, we investigate an unusual Acr, AcrIF9, that induce...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Lu, Wang-Ting, Trost, Chantel N, Müller-Esparza, Hanna, Randau, Lennart, Davidson, Alan R
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8034650/
https://ncbi.nlm.nih.gov/pubmed/33660777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab092
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