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Structural basis for inhibition of the type I-F CRISPR–Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14

CRISPR–Cas systems are adaptive immune systems in bacteria and archaea to defend against mobile genetic elements (MGEs) and have been repurposed as genome editing tools. Anti-CRISPR (Acr) proteins are produced by MGEs to counteract CRISPR–Cas systems and can be used to regulate genome editing by CRI...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Gabel, Clinton, Li, Zhuang, Zhang, Heng, Chang, Leifu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797054/
https://ncbi.nlm.nih.gov/pubmed/33332569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1199
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