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Structural basis for inhibition of the type I-F CRISPR–Cas surveillance complex by AcrIF4, AcrIF7 and AcrIF14

CRISPR–Cas systems are adaptive immune systems in bacteria and archaea to defend against mobile genetic elements (MGEs) and have been repurposed as genome editing tools. Anti-CRISPR (Acr) proteins are produced by MGEs to counteract CRISPR–Cas systems and can be used to regulate genome editing by CRI...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: Gabel, Clinton, Li, Zhuang, Zhang, Heng, Chang, Leifu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797054/
https://ncbi.nlm.nih.gov/pubmed/33332569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1199
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