PAM identification by CRISPR-Cas effector complexes: diversified mechanisms and structures

Adaptive immunity of prokaryotes is mediated by CRISPR-Cas systems that employ a large variety of Cas protein effectors to identify and destroy foreign genetic material. The different targeting mechanisms of Cas proteins rely on the proper protection of the host genome sequence while allowing for ef...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:RNA Biol
Main Authors: Gleditzsch, Daniel, Pausch, Patrick, Müller-Esparza, Hanna, Özcan, Ahsen, Guo, Xiaohan, Bange, Gert, Randau, Lennart
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2018
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546366/
https://ncbi.nlm.nih.gov/pubmed/30109815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2018.1504546
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