Methylation-dependent Tissue Factor suppression contributes to the reduced malignancy of IDH1 mutant gliomas

PURPOSE: Gliomas with isocitrate dehydrogenase 1 mutations (IDH1(mut)) are less aggressive than IDH1 wild-type (IDH1(wt)) gliomas and have global genomic hypermethylation. Yet it is unclear how specific hypermethylation events contribute to the IDH1(mut) phenotype. Previously, we showed that the gen...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Unruh, Dusten, Mirkov, Snezana, Wray, Brian, Drumm, Michael, Lamano, Jonathan, Li, Yuping D, Haider, Qazi F., Javier, Rodrigo, McCortney, Kathleen, Saratsis, Amanda, Scholtens, Denise M., Sarkaria, Jann N., James, C. David, Horbinski, Craig
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537089/
https://ncbi.nlm.nih.gov/pubmed/30266764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1222
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados