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Methylation-dependent Tissue Factor suppression contributes to the reduced malignancy of IDH1 mutant gliomas
PURPOSE: Gliomas with isocitrate dehydrogenase 1 mutations (IDH1(mut)) are less aggressive than IDH1 wild-type (IDH1(wt)) gliomas and have global genomic hypermethylation. Yet it is unclear how specific hypermethylation events contribute to the IDH1(mut) phenotype. Previously, we showed that the gen...
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| Udgivet i: | Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6537089/ https://ncbi.nlm.nih.gov/pubmed/30266764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-1222 |
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