STEM-28. TISSUE FACTOR PROMOTES THE GLIOMA STEM CELL PHENOTYPE, AND IS SUPPRESSED BY MUTANT IDH1

Isocitrate dehydrogenase 1 mutant (IDH1(mut)) gliomas have global genomic hypermethylation, are less aggressive than IDH1 wild-type (IDH1(wt)) gliomas, and generally grow poorly in vitro and in vivo. Yet little data exist that connect specific hypermethylation targets to this unique phenotype. We pr...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Unruh, Dusten, Mirkov, Snezana, Wray, Brian, Lamano, Jonathan, Scholtens, Denise M, Sarkaria, Jann N, James, C David, Horbinski, Craig
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2018
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Abstracts
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216244/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1035
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