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STEM-28. TISSUE FACTOR PROMOTES THE GLIOMA STEM CELL PHENOTYPE, AND IS SUPPRESSED BY MUTANT IDH1

Isocitrate dehydrogenase 1 mutant (IDH1(mut)) gliomas have global genomic hypermethylation, are less aggressive than IDH1 wild-type (IDH1(wt)) gliomas, and generally grow poorly in vitro and in vivo. Yet little data exist that connect specific hypermethylation targets to this unique phenotype. We pr...

詳細記述

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書誌詳細
出版年:Neuro Oncol
主要な著者: Unruh, Dusten, Mirkov, Snezana, Wray, Brian, Lamano, Jonathan, Scholtens, Denise M, Sarkaria, Jann N, James, C David, Horbinski, Craig
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6216244/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.1035
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