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Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers
Mutations in isocitrate dehydrogenases 1 and 2 (IDH(mut)) are present in a variety of cancers, including glioma, acute myeloid leukemia (AML), melanoma, and cholangiocarcinoma. These mutations promote hypermethylation, yet it is only a favorable prognostic marker in glioma, for reasons that are uncl...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6586617/ https://ncbi.nlm.nih.gov/pubmed/31222125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45346-1 |
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