Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma

Mast cells (MC) have been identified in human lung adenocarcinoma (LADC) tissues, but their functional role has not been investigated in vivo. For this, we applied three mouse models of KRAS-mutant LADC to two different MC-deficient mouse strains (cKit(Wsh) and Cpa3.Cre). Moreover, we derived MC gen...

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Detaylı Bibliyografya
Yayımlandı:Oncoimmunology
Asıl Yazarlar: Lilis, Ioannis, Ntaliarda, Giannoula, Papaleonidopoulos, Vassilios, Giotopoulou, Georgia A, Oplopoiou, Maria, Marazioti, Antonia, Spella, Magda, Marwitz, Sebastian, Goldmann, Torsten, Bravou, Vasiliki, Giopanou, Ioanna, Stathopoulos, Georgios T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2019
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6527299/
https://ncbi.nlm.nih.gov/pubmed/31143511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1593802
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