Beneficial Impact of CCL2 and CCL12 Neutralization on Experimental Malignant Pleural Effusion

Using genetic interventions, we previously determined that C-C motif chemokine ligand 2 (CCL2) promotes malignant pleural effusion (MPE) formation in mice. Here we conducted preclinical studies aimed at assessing the specific therapeutic potential of antibody-mediated CCL2 blockade against MPE. For...

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Main Authors: Marazioti, Antonia, Kairi, Chrysoula A., Spella, Magda, Giannou, Anastasios D., Magkouta, Sophia, Giopanou, Ioanna, Papaleonidopoulos, Vassilios, Kalomenidis, Ioannis, Snyder, Linda A., Kardamakis, Dimitrios, Stathopoulos, Georgios T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3743892/
https://ncbi.nlm.nih.gov/pubmed/23967166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071207
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