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Interleukin-1β provided by KIT-competent mast cells is required for KRAS-mutant lung adenocarcinoma
Mast cells (MC) have been identified in human lung adenocarcinoma (LADC) tissues, but their functional role has not been investigated in vivo. For this, we applied three mouse models of KRAS-mutant LADC to two different MC-deficient mouse strains (cKit(Wsh) and Cpa3.Cre). Moreover, we derived MC gen...
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| Publié dans: | Oncoimmunology |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6527299/ https://ncbi.nlm.nih.gov/pubmed/31143511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1593802 |
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