IκB kinase α is required for development and progression of KRAS-mutant lung adenocarcinoma

Although oncogenic activation of nuclear factor (NF)-κB has been identified in various tumors, the NF-κB-activating kinases (inhibitor of NF-κB kinases, IKK) responsible for this are elusive. In this study, we determined the role of IKKα and IKKβ in KRAS-mutant lung adenocarcinomas induced by the ca...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Vreka, Malamati, Lilis, Ioannis, Papageorgopoulou, Maria, Giotopoulou, Georgia A., Lianou, Marina, Giopanou, Ioanna, Kanellakis, Nikolaos I., Spella, Magda, Agalioti, Theodora, Armenis, Vasileios, Goldmann, Torsten, Marwitz, Sebastian, Yull, Fiona E., Blackwell, Timothy S., Pasparakis, Manolis, Marazioti, Antonia, Stathopoulos, Georgios T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485619/
https://ncbi.nlm.nih.gov/pubmed/29588349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-1944
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